Research: RNA and DNA biochemistry, chemical modification of nucleic acids, cell biology, delivery of oligonucleotides to cells and animal models, fluorescence microscopy, atomic force microscopy (AFM) of nucleic acids.
The DNA 'origami' method was extended into 3D to create an addressable DNA box on the nanometre scale that can be opened by externally supplied DNA 'keys'. The study appeared online in Nature, May 6, 2009:
